MICROENCAPSULATED

TRHOUGH SPRAY DRYER

Encapsulation is a process where a substance or active ingredient is coated with another protective substance of a different nature. In the case of active encapsulation using a spray dryer, small droplets generated by atomization are used to facilitate rapid drying. This reduces the degradation of the encapsulated components.

Advantages of microencapsulation:

1. Improved preservation and stability: Protects active ingredients during storage against external factors such as light, oxygen, temperature, and pH.

2. Extended release: Allows continuous or sustained dosing over time.

3. Selective release: Activates under specific conditions, such as pH changes or mechanical stress.

4. Masking of odors and flavors: Ideal for ingredients with unpleasant odor or taste.

TRHOUGH PHYSICAL & CHEMICAL METHODS

Encapsulation by solid coating through a chemical reaction with fatty acids (lipid encapsulation):

1. Solid coating: This method involves forming a solid layer around the active material. In your case, the liquid fatty acid is converted into a solid layer through a chemical reaction.

2. Chemical reaction pathway: Solidification is achieved through a chemical reaction between the fatty acid (lauric or palmitic acid) and calcium hydroxide, resulting in the formation of calcium laurate or palmitate, which acts as a protective layer.

3. Lipid encapsulation: You use fatty acids such as lauric or palmitic acid to encapsulate the actives. This method is typical of lipid encapsulation, where lipids are used to form a barrier around the actives.

ADSORPTION DRYING 

This method consists of mixing the liquid active ingredient with a carrier material until the liquid is absorbed and the mixture dries, resulting in a solid form.

The liquid is mixed with maltodextrin (or another absorbent excipient), which acts as a drying and adsorbing agent, until all the moisture from the liquid is absorbed, forming a dry powder.